This is really heady stuff.
Here is a two and a half hour round table discussion on audio fidelity, set up by the Philoctetes Center (The Multidisciplinary Study of Imagination).
On the surface it seems to be a bunch of mastering engineers ragging on digital audio (and specifically MP3), but there are some great observations on the science of audio, and the business of production.
Participants: Steve Berkowitz, Greg Calbi (moderator), Evan Cornog, Michael Fremer, Kevin Killen, Craig Street
Deep Listening: Why Audio Quality Matters
The irony of course is that the audio of the discussion is really poor...